Zhuoya Wan
Eco Science Journals
Editor Name: Zhuoya Wan
Designation: Research Fellow
Country: USA, Pennsylvania
University: University of Pittsburgh School of Pharmacy
Email: zhw64@pitt.edu
Research Interest: Drug Delivery, Immunology, Computational Biology Cancer
Immunotherapy, Leukemia
BIOGRAPHY:
Zhuoya Wan is a researcher of
Pharmaceutical Science in Pharmaceutics and Immunology at the University of
Pittsburgh, School of Pharmacy. Wan is the recipient of the graduate student
excellence award at University of Pittsburgh and selective oral presentation
award at the ACS National Meeting, America Society of Chemistry. In addition,
Wan is also a peer reviewer in BMC cancer, Cancer Biology& Therapy, and
Bioscience Reports.
EDUCATION BACKGROUND
University of Pittsburgh (PITT)
08/2017-Present PhD student, Pharmaceutical Science, Advisor: Song LiCenter for Pharmacogenetics, School of Pharmacy,
University of Pittsburgh
University of Pittsburgh (PITT)
08/2016-08/2017
M.S., Pharmaceutics, Advisor: Song Li Center for Pharmacogenetics, School of Pharmacy,
University of Pittsburgh
SiChuan University (SCU) 09/2011-09/2015
B.S., Pharmacy, Advisor: Zhirong Zhang and Yuan Huang
Sichuan
University,West China School of Pharmacy
Positions and Employments
Research Fellow, Center for Pharmacogenetics, Department of Pharmaceutical Science,
University of Pittsburgh School of Pharmacy, USA 2016-Present
Research Assistant, Key Lab of Drug Targeting and Drug Delivery Systems, West China School
of Pharmacy, Sichuan University, China
SELECTED AWARDS & HONORS
1. Graduate
Student Excellence Award ($2000), University of Pittsburgh, 2020
2. Selective
Oral Presentation Award ($225), ACS National Meeting, America Society of
Chemistry, 2019
3. Featured
Media Interview: An interview with Zhuoya Wan in Cancer Immunotherapy, RxNet
London, 2019
4. PITT-GPSG
Travel Grant, University of Pittsburgh, 2019
5. Graduate
Program Council (GPC) Travel Award, PITT School of Pharmacy, 2019
6. Editor of
AAPS Pitt Student Chapter Newspaper 2018-2020 (Chief Editor in 2020)
7. Research
Fellowship, University of Pittsburgh (2016-present)
8. Teaching
Fellowship, University of Pittsburgh (2016-present)
9. National
Scholarship (2012), Ministry of Education of China
10. First
Class Scholarship (2012, 2014); Second Class Scholarship (2013), Sichuan
University
11. National
Undergraduate Research Achievement (2014), First Prize, China Association
Higher Education
12. National
Excellent Research Project Leader (2014), Innovation Program
13. Best
Oral Presentation award of Medical Group, Top-3 Outstanding Oral Presentation
Award, Annual Conference of Undergraduate Innovation and Entrepreneurship
(2014), Sichuan University
14. Research
essay was finally rewarded First Prize, Innovation Program (2014), Sichuan
University
15.
Excellent Graduation Project (2015), Sichuan University
16.
Excellent Student Leader for Science Department (2014), Sichuan University
17. Excellent
Student Leader of Academic Association (2013), Sichuan University
18. Founder
and President of Drug Delivery System (DDS) Research Association in Sichuan
University
PROFESSIONAL ACTIVITIES
Academic Members and Employments
Chair, American
Association of Pharmaceutical Scientist (AAPS), PITT Student Chapter
(2017-2020)
Committee Member, Graduate and Professional Student Organization, PITT (2017-2019)
Committee Member, sub-group leader in restart-research group (COVID-9 Hazard Assessment),
2020
American
Association for the Advancement of Science (AAAS)
American
Association of Pharmaceutical Scientist (AAPS)
Controlled
Release Society (CRS)
American
Chemical Society (ACS)
The American
Institute of Chemical Engineers (AIChE)
PUBLICATIONS
GoogleScholar:
https://scholar.google.com/citations?user=0ssHBk0AAAAJ&hl=en&oi=ao
1. Zhuoya Wan, Jingjing Sun, Dual
Functional Immunostimulatory Polymeric Prodrug Carrier with Pendent Indoximod
for Enhanced Cancer Immunochemotherapy; Acta Biomaterialia., 90, 300-313, 2019
IF=7.2
2. Jingjing Sun*, Zhuoya Wan*, Jieni
Xu* (Co-first author), Song Li, Tumor Size-Dependent Abscopal Effect of
Polydopamine-coated NPs Co-loaded with Gemcitabine and IDO Inhibitor for
Immunochemo-photothermal Therapy, Biomaterials, 2020 IF=10.2
3. Zhuoya Wan, Xu Song, Qiang Ao,
Recent Advancement of Nanomedicine, Immunotherapy and Combination Therapy for
Leukemia, Journal of Leukocyte Biology, 2020 (In Press) IF=4.3
4. Zhuoya Wan, Pearl Moharil, Ruohui
Zheng, Polymeric Micelles in Cancer Immunotherapy, Molecules, 2021(In Press)
IF=3.267
5. Zhuoya Wan, Zhang Fan, Yang Rui, Ma
Shanfu, Huang Yuan, The impact of different molecular weights of trimethyl
chitosan on insulin-loaded chitosan nanoparticles, West China Journal of
Pharmaceutical Sciences., 2016; Zhuoya., Wan et al., collected by National 7th
Chinese Pharmaceutical Students’ Creativity Forum (conference paper)., 31 (3),
227-229, 2016
6. Jingjing Sun, Zhuoya Wan, Triple
Drugs Co-Delivered by a Small Gemcitabine-Based Carrier for Pancreatic Cancer
Immunochemotherapy; Acta Biomaterialia., 106, 289-300, 2020 IF=6.4
7. Xu Song, Zhuoya Wan, Lin Li, Xun
Sun, Tao Gong, Zhirong Zhang, A multi-target peptide for potentiating
chemotherapy by modulating tumor microenvironment; Biomaterials., 108, 44-56,
2017 IF=10.3
8. Juan Zhao, Zhuoya Wan, Chuchu Zhou,
Qin Yang, Jianxia Dong, Xu Song, Tao Gong, Hyaluronic Acid Layer-By-Layer (LbL)
Nanoparticles for Synergistic Chemo-Phototherapy, Pharmaceutical Research., 35
(10), 196, 2019 IF=3.4
9. Jingjing Sun, Yichao Chen, Jieni Xu,
Xiangping Song, Zhuoya Wan, High Loading of Hydrophobic and Hydrophilic Agents
via Small Immunostimulatory Carrier for Enhanced Tumor Penetration and
Combinational Therapy, Theranostics., 10 (3), 1136, 2020 IF=8.7
10. Jingjing Sun, Lingyi Sun, Jianchun
Li, Jieni Xu, Zhuoya Wan, A multi-functional polymeric carrier for simultaneous
positron emission tomography imaging and combination therapy, Acta
Biomaterialia., 75, 312-322, 2018 IF=6.4
11. Kejun Jiang, Xu Song, Liuqing Yang,
Lin Li, Zhuoya Wan, Xun Sun, Tao Gong, Qing Lin, Zhirong Zhang, Enhanced
antitumor and anti-metastasis efficacy against aggressive breast cancer with a
fibronectin-targeting liposomal doxorubicin; Journal of Controlled Release.,
271, 21-30, 2018 IF=7.9
12. Qin Yang, Tiantian Tan, Juan Zhao,
Chuchu Zhou, Chenqi Guo, Zhuoya Wan, Xu Song, Tao Gong., A reversible
decomposition approach for the formation of injectable, excipient‐free, self‐assembling nanocrystals, Chemical
Communications., 55 (21), 3144-3147, 2019 IF=6.16
13. Zhangyi Luo, Jieni Xu, Jingjing
Sun, Haozhe Huang, Ziqian Zhang, Weina Ma, Zhuoya Wan, Co-delivery of
2-Deoxyglucose and a glutamine metabolism inhibitor V9302 via a prodrug
micellar formulation for synergistic targeting of metabolism in cancer; Acta
Biomaterialia., 105, 239-252, 2020 IF=6.4
14. Yanhua Liu; Jingjing Sun; Yixian
Huang; Yichao Chen; Jiang Li; Lei Liang; Jieni Xu; Zhuoya Wan; Bei Zhang;
Zuojun Li, Song Li; Metformin-conjugated micellar system with intratumoral pH
responsive de-shielding for co-delivery of doxorubicin and nucleic acid,
Biochemical Pharmacology., 2021
15. Xiaoli Yi, Xianghong Lian, Jianxia
Dong, Zhuoya Wan, Chunyu Xia, Xu Song, Yao Fu, Tao Gong, Zhirong Zhang,
Co-delivery of pirarubicin and paclitaxel by human serum albumin nanoparticles
to enhance antitumor effect and reduce systemic toxicity in breast cancers;
Molecular Pharmaceutics., 12 (11), 4085-4098, 2015 IF=4.4
16. Chuchu Zhou, Chenqi Guo, Wenhao Li,
Juan Zhao, Qin Yang, Tiantian Tan, Zhuoya Wan, Jianxia Dong, Xu Song, Tao
Gong., A novel honokiol liposome: formulation, pharmacokinetics, and antitumor
studies, Drug Development and Industrial Pharmacy., 44 (12), 2005-2012, 2018
IF=2.3
17. Xu Song, Huan Liu, Qin Yang, Zhuoya
Wan, Xun Sun, Tao Gong, Zhirong Zhang, A Submicron Emulsion for Intravenous
Injection of 7-Ethyl-10-Hydroxycamptothecin: Characterization, Pharmacokinetic
and Biodistribution Studies, In Vitro and In Vivo Antitumor Effect, Latin
American Journal of Pharmacy., 35 (6), 1369-1377, 2016
Selected Oral presentations
1. Podium Award, 12th Annual
Pharmaceutical Sciences Research Symposium, Targeting Metabotropic Glutamate
Receptor 4 for Cancer Immunotherapy, American Association of Pharmaceutical
Scientist (Pitt-Duq-WVU), March, 2021 *Ranked 1st in the Section of
Pharmacology
2. Ten-minutes On-Demand Talk, Control
Release Society Annual Meeting, Rational Design of An AraC-Based Ultrasmall
Prodrug Nanocarrier for Effective Leukemia Combination Therapy, Virtual
Meeting, July, 2020
3. Podium Award, 11th Annual
Pharmaceutical Sciences Research Symposium, Triple drugs co-delivered by a
small AraC-based carrier for leukemia immunochemotherapy, American Association
of Pharmaceutical Scientist (Pitt-Duq-WVU), January, 2020
4. Oral Presentation, 2019 AIChE Annual
Meeting, Biomaterials for Immunological Applications, Dual Functional
Immunostimulatory Polymeric Prodrug Carrier with Pendent Indoximod for Enhanced
Cancer Immunochemotherapy, Orlando, November, 2019
5. Invited Oral Presentation, 2019 Cell
Therapies and Immunotherapy Conference, Society for Biological Engineering,
AIChE Dual Functional Immunostimulatory Polymeric Prodrug Carrier with Pendent
Indoximod for Enhanced Cancer Immunochemotherapy, San Francisco, October, 2019
6. Oral Presentation, ACS Fall 2019
National Meeting & Exposition, Dual Functional Immunostimulatory Polymeric
Prodrug Carrier with Pendent Indoximod for Enhanced Cancer Immunochemotherapy,
American Chemical Society, San Diego, August, 2019
7. Podium Award, 8th National Chinese
Pharmaceutical Students’ Creativity Forum, The impact of different molecular
weights of trimethyl chitosan on insulin-loaded chitosan nanoparticles, China
Pharmaceutical University, Nanjing, November, 2015
8. Podium Award, 7th National Chinese
Pharmaceutical Students’ Creativity Forum, The impact of different molecular
weights of trimethyl chitosan on insulin-loaded chitosan nanoparticles,
Guangdong Pharmaceutical University, Guangzhou, November, 2014
9. Podium Award, Undergraduate Innovation Forum of Sichuan University, The impact of different molecular weights of trimethyl chitosan on insulin-loaded chitosan nanoparticles, August, 2014